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Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!2025-02-06
350 Results for "
Ficus sarmentosa var. nipponica (Fr.et Sav.)Corner
" in MedChemExpress (MCE) Product Catalog:
Products (350)
350 Results for "Ficus sarmentosa var. nipponica (Fr.et Sav.)Corner" in MCE Product Catalog:
22
22 Publications Verification
Target:
Forschungsgebiete:
AZD-5991 is a potent and selective Mcl-1 inhibitor with an IC50 of 0.7 nM in FRET assay and a Kd of 0.17 nM in surface plasmon resonance (SPR) assay .
20
20 Cited Publications
Art. -Nr.: HY-N0009
CAS. Nr.: 24512-63-8
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10
10 Cited Publications
Art. -Nr.: HY-N2019
CAS. Nr.: 28097-03-2
7
7 Cited Publications
Forschungsgebiete:
GNE-049 is a highly potent and selective CBP inhibitor with an IC50 of 1.1 nM in TR-FRET assay. GNE-049 also inhibits BRET and BRD4(1) with IC50s of 12 nM and 4200 nM, respectively .
6
6 Cited Publications
Forschungsgebiete:
GNE-781 is an orally active, highly potent and selective CBP inhibitor with an IC50 of 0.94 nM in TR-FRET assay. GNE-781 also inhibits BRET and BRD4(1) with IC50s of 6.2 nM and 5100 nM, respectively. GNE-781 displays antitumor activity in an MOLM-16 AML xenograft model .
4
3
3 Cited Publications
Synonyms: trans-PX-102
Forschungsgebiete:
PX20606 trans racemate (PX-102 trans racemate) is a FXR agonist with EC50s of 32 and 34 nM for FXR in FRET and M1H assay, respectively .
3
3 Cited Publications
Art. -Nr.: HY-162289
CAS. Nr.: 3036029-78-1
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Forschungsgebiete:
FAZ-3780 is an inhibitor that binds to the NTF2L domain of G3BP1/2. FAZ-3780 binds to the NTF2L nsP3 of G3BP1 with high affinity, with a Kd of 0.15 μM and a Pep-FRET IC50 of 0.7 μM. FAZ-3780 targets the protein-protein interaction domain of G3BP1/2, and specifically inhibits the co-condensation of G3BP1, caprin 1 and RNA in vitro. FAZ-3780 inhibits stress granule formation and disassembles pre-formed stress granules. FAZ-3780 can be used in studies related to cancer and neurodegenerative diseases .
2
2 Cited Publications
Forschungsgebiete:
GSK 4027 is a chemical probe for the PCAF/GCN5 bromodomain with an pIC50 of 7.4±0.11 for PCAF in a time-resolved fluorescence resonance energy transfer (TR-FRET) assay.
2
2 Cited Publications
Art. -Nr.: HY-N2112
CAS. Nr.: 79498-31-0
2
2 Cited Publications
Synonyms: 5-Deoxykampferol; Resokaempferol
1
1 Cited Publications
Art. -Nr.: HY-P5354
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Forschungsgebiete:
1
Category:
Target:
1
1 Cited Publications
Art. -Nr.: HY-N3857
CAS. Nr.: 63807-85-2
Target:
1
1 Cited Publications
Art. -Nr.: HY-P5354A
Target:
Forschungsgebiete:
1
1 Cited Publications
Art. -Nr.: HY-161159
CAS. Nr.: 2322286-81-5
Target:
Forschungsgebiete:
DMHBO+ is a cationic chromophore that binds to the Chili aptamer with a Kd of 12 nM. The Chili-DMHBO+ complex is an ideal fluorescence donor for FRET to the rhodamine dye Atto 590, suitable for imaging RNA in cells. Ex/Em=456/592 nm .
1
1 Cited Publications
Forschungsgebiete:
GSK4028 is the enantiomeric negative control of GSK4027, which is a PCAF/GCN5 bromodomain chemical probe, the pIC50 of GSK4028 is 4.9 in a time-resolved fluorescence resonance energy transfer (TR-FRET) assay.
1
1 Cited Publications
Art. -Nr.: HY-15943
CAS. Nr.: 91809-67-5
Synonyms: 6-Carboxytetramethylrhodamine
1
1 Cited Publications
Art. -Nr.: HY-D1050
CAS. Nr.: 82321-04-8
Synonyms: 6-(2,4-Dinitrophenyl)aminohexanoic acid, succinimidyl ester
1
1 Cited Publications
Art. -Nr.: HY-B0856
CAS. Nr.: 37248-47-8
Category:
Infection Microorganisms Antibiotics Disease Research Antibacterial Disease Research Fields Other Antibiotics
Target:
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Protocols
Targeted therapy! The Capetin Prize winning "Click Chemistry" can be used like this!Targeted therapy! The Nobel Prize winning "Click Chemistry" can be used like this!A suitable model is crucial in drug screening experiments. Organs can mimic the three-dimensional functional structure of internal organs, have similar spatial organization to corresponding organs, maintain some key characteristics, and reproduce some physiological functions. They are widely used for modeling and personalized drug screening physiological functions.2025-02-06
